Stanford-SLAC Cryo-EM Center

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منابع مشابه

SLAC-PUB-95-6749 (March 1995) PERSPECTIVES OF PERSONNEL EXTERNAL DOSIMETRY AT STANFORD LINEAR ACCELERATOR CENTER

J. C. Liu, D. Busick1, K. R. Kase, R. C. McCall2, R. Sit and H. Tran3 Stanford Linear Accelerator Center, P. O. Box 4349, Stanford, CA 94309 Abstract The need for providing personnel external monitoring for exposure to lowenergy photon (< 150 keV) and beta radiation at the Stanford Linear Accelerator Center (SLAC) has been studied. At SLAC, a high energy electron accelerator facility, the major...

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Cryo-EM enters a new era

Advances in detector hardware and image-processing software have led to a revolution in the use of electron cryo-microscopy to determine complex molecular structures at high resolution.

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Cryo-EM structure of a transcribing cypovirus.

Double-stranded RNA viruses in the family Reoviridae are capable of transcribing and capping nascent mRNA within an icosahedral viral capsid that remains intact throughout repeated transcription cycles. However, how the highly coordinated mRNA transcription and capping process is facilitated by viral capsid proteins is still unknown. Cypovirus provides a good model system for studying the mRNA ...

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Cryo-EM of viruses and vaccine design.

Knowledge of the atomic resolution structures of viruses can be a powerful tool for vaccine discovery and design. X-ray crystallography has long served as an invaluable method for virus structure determination at high resolution, but over the past decade, cryoelectron microscopy (cryo-EM) has begun to emerge as a complementary method that can also provide this kind of information. Crystallograp...

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Single-Particle Cryo-EM at Crystallographic Resolution

Until only a few years ago, single-particle electron cryo-microscopy (cryo-EM) was usually not the first choice for many structural biologists due to its limited resolution in the range of nanometer to subnanometer. Now, this method rivals X-ray crystallography in terms of resolution and can be used to determine atomic structures of macromolecules that are either refractory to crystallization o...

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ژورنال

عنوان ژورنال: Acta Crystallographica Section A Foundations and Advances

سال: 2020

ISSN: 2053-2733

DOI: 10.1107/s0108767320098025